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验证数据展示

  • WB analysis using 20851-1-AP (same clone as 20851-1-PBS)

    WB analysis using 20851-1-AP (same clone as 20851-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20851-1-AP (GRINA antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20851-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 20851-1-AP (same clone as 20851-1-PBS)

    IHC staining of human placenta using 20851-1-AP (same clone as 20851-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 20851-1-AP (GRINA antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20851-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GRINA antibody included
  • IHC staining of human placenta using 20851-1-AP (same clone as 20851-1-PBS)

    IHC staining of human placenta using 20851-1-AP (same clone as 20851-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 20851-1-AP (GRINA antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20851-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GRINA antibody included

GRINA Polyclonal antibody, PBS Only

GRINA Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 20851-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

Glutamate [NMDA] receptor-associated protein 1, HNRGW, LFG1, Protein lifeguard 1, Putative MAPK-activating protein PM02

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy® GRINA Ready-To-Use IHC Kit. GRINA primary antibody included.

产品信息

20851-1-PBS targets GRINA in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag14716

Product name: Recombinant human GRINA protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-170 aa of BC041788

Sequence: MSHEKSFLVSGDNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYPQGPYPQEGYPQGPYPQGGYPQGPYPQNPFPPNPYGQPQVFPGQDPDSPQHGNYQEEGPPSYYDNQDFPATNWDDKSIRQAFIRKVFLVLT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
别名 Glutamate [NMDA] receptor-associated protein 1, HNRGW, LFG1, Protein lifeguard 1, Putative MAPK-activating protein PM02
计算分子量 371 aa, 41 kDa
观测分子量49 kDa
GenBank蛋白编号BC041788
基因名称 GRINA
Gene ID (NCBI) 2907
RRIDAB_3742005
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ7Z429
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Glutamate Receptor Ionotropic NMDA-Associated Protein 1 (GRINA, also known as TMBIM3) is a transmembrane protein involved in calcium homeostasis and cell survival. It plays a crucial role in regulating intracellular calcium levels, which are essential for processes such as cell survival, neurotransmitter release, and apoptosis (PMID: 32124700). GRINA also involves vesicle transport and sorting, particularly in secretory cells like neurons and mammary glands (PMID: 31426446). Additionally, GRINA has been implicated in regulating aerobic glycolysis and tumor progression in gastric cancer (PMID: 30541591).

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