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CoraLite® Plus 488-conjugated TMEM173/STING Recombinant antibody

TMEM173/STING Recombinant Antibody for IF-P

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse, Rat

Applications

IF-P

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

7K7

Cat No : CL488-80165

Print datasheet

Synonyms

FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, MPYS, STING, TMEM173, transmembrane protein 173

验证数据展示

  • IF Staining of human tonsillitis using CL488-80165

    IF Staining of human tonsillitis using CL488-80165

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite® Plus 488 TMEM173/STING antibody (CL488-80165, Clone: 7K7 ) at dilution of 1:200.

  • IF Staining of human tonsillitis using CL488-80165

    IF Staining of human tonsillitis using CL488-80165

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite® Plus 488 TMEM173/STING antibody (CL488-80165, Clone: 7K7 ) at dilution of 1:200.

经过测试的应用

Positive IF detected inhuman tonsillitis tissue
Planning an IHC experiment? We recommend our IHCeasy STING Ready-To-Use IHC Kit. STING primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 80165-1-PBS

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-80165 targets TMEM173/STING in IF applications and shows reactivity with Human, Mouse, Rat samples.

Tested Applications IF-P
Tested Reactivity Human, Mouse, Rat
Immunogen TMEM173/STING fusion protein Ag13921 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name transmembrane protein 173
Synonyms FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, MPYS, STING, TMEM173, transmembrane protein 173
Calculated Molecular Weight 379 aa, 42 kDa
Observed Molecular Weight37 kDa
GenBank Accession NumberBC047779
Gene Symbol TMEM173
Gene ID (NCBI) 340061
RRIDAB_2919576
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ86WV6
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

背景介绍

Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TMEM173/STING antibody CL488-80165Download protocol
Standard Protocols
Click here to view our Standard Protocols