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TMEM173/STING Recombinant antibody, PBS Only

TMEM173/STING Recombinant Antibody for WB,IP,Indirect ELISA,IHC,IF

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse, Rat

Applications

WB,IP,Indirect ELISA,IHC,IF

Conjugate

Unconjugated

CloneNo.

7K7

Cat No : 80165-1-PBS

Print datasheet

Synonyms

FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, MPYS, NET23, STING, TMEM173, TMEM173/STING, transmembrane protein 173

验证数据展示

  • WB analysis using 80165-1-RR (same clone as 80165-1-PBS)

    WB analysis using 80165-1-RR (same clone as 80165-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 80165-1-RR (TMEM173/STING antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 80165-1-RR (same clone as 80165-1-PBS)

    IP experiment of HeLa using 80165-1-RR (same clone as 80165-1-PBS)

    IP result of anti-TMEM173/STING (IP: 80165-1-RR, 4ug; Detection: 80165-1-RR 1:8000) with HeLa cells lysate 1800 ug. This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    IHC staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 80165-1-RR (TMEM173/STING antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with STING antibody included
  • IHC staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    IHC staining of human tonsillitis using 80165-1-RR (same clone as 80165-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 80165-1-RR (TMEM173/STING antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with STING antibody included
  • IF Staining of THP-1 using 80165-1-RR (same clone as 80165-1-PBS)

    IF Staining of THP-1 using 80165-1-RR (same clone as 80165-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using TMEM173/STING antibody (80165-1-RR, Clone: 7K7 ) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 80165-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy STING Ready-To-Use IHC Kit. STING primary antibody included.

产品信息

80165-1-PBS targets TMEM173/STING in WB, IP, IF, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Applications WB,IP,Indirect ELISA,IHC,IF
Tested Reactivity Human, Mouse, Rat
Immunogen TMEM173/STING fusion protein Ag13921 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name transmembrane protein 173
Synonyms FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, MPYS, NET23, STING, TMEM173, TMEM173/STING, transmembrane protein 173
Calculated Molecular Weight 379 aa, 42 kDa
Observed Molecular Weight37 kDa
GenBank Accession NumberBC047779
Gene Symbol TMEM173
Gene ID (NCBI) 340061
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ86WV6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines.