验证数据展示
产品信息
68126-1-PBS targets RBP5 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, pig samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, pig |
免疫原 | RBP5 fusion protein Ag24562 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | retinol binding protein 5, cellular |
别名 | CRBP III, CRBP3, CRBPIII, HRBPiso, RBP5, Retinol binding protein 5 |
计算分子量 | 135 aa, 16 kDa |
观测分子量 | 16-18 kDa |
GenBank蛋白编号 | BC029355 |
基因名称 | RBP5 |
Gene ID (NCBI) | 83758 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P82980 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RBP5 (CRBP III) belongs to the fatty-acid binding protein (FABP) family. Human liver and kidney contain the highest levels of CRBP III mRNA, and CRBP III is as a major human intracellular carrier of retinol (PMID:11274389). RBP5 iron response are reversible by genetic complementation. And increased RBP5 expression occurs by a post-transcriptional feedback mechanism whereby RBP5 interacts with its own, and with PAP2 mRNAs. RBP5 is the most significant of the proteins upregulated by iron starvation (PMID:34161395). RBP5 has an estimated molecular mass (15.9 kDa) typical of this protein superfamily (PMID:11274389).