Phospho-STK11/LKB1 (Thr189) Recombinant antibody
Phospho-STK11/LKB1 (Thr189) Recombinant Antibody for FC, IF, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, Mouse
Applications
FC, IF, WB, ELISA
Conjugate
Unconjugated
CloneNo.
5J9
验证数据展示
经过测试的应用
Positive WB detected in | PC-3 cells, HEK-293 cells, NIH/3T3 cells, Calyculin A treated HEK-293 cells, Calyculin A treated PC-3 cells, Calyculin A treated NIH/3T3 cells |
Positive IF detected in | Calyculin A treated PC-3 cells |
Positive FC detected in | Calyculin A treated PC-3 cells |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:1000-1:10000 |
Immunofluorescence (IF) | IF : 1:50-1:500 |
Sample-dependent, check data in validation data gallery |
产品信息
80127-1-RR targets Phospho-STK11/LKB1 (Thr189) in WB, IF, FC, ELISA applications and shows reactivity with Human, Mouse samples.
Tested Applications | FC, IF, WB, ELISA |
Tested Reactivity | Human, Mouse |
Immunogen | Peptide 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | serine/threonine kinase 11 |
Synonyms | LKB1, Phospho-STK11 (Thr189), PJS, serine/threonine kinase 11, STK11 |
Calculated molecular weight | 49 kDa |
Observed molecular weight | 50-55 kDa |
GenBank accession number | BC007981 |
Gene symbol | STK11 |
Uniprot | Q15831 |
Gene ID (NCBI) | 6794 |
RRID | AB_2918867 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
STK11(serine/threonine-protein kinase 11) is also named as LKB1, PJS, and belongs to the protein kinase superfamily. It controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. The tumour suppressor protein LKB1 is a serine/threonine kinase that has been causally linked to Peutz-Jeghers syndrome (PJS). Defects in STK11 are a cause of Peutz-Jeghers syndrome (PJS) and defects in STK11 have been associated with testicular germ cell tumor (TGCT) and some sporadic cancers, especially lung cancers.
实验方案
Product Specific Protocols | |
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WB protocol for Phospho-STK11/LKB1 (Thr189) antibody 80127-1-RR | Download protocol |
IF protocol for Phospho-STK11/LKB1 (Thr189) antibody 80127-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |