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验证数据展示

  • IF Staining of MCF-7 using CL488-18884

    IF Staining of MCF-7 using CL488-18884

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using CoraLite® Plus 488 Glutaredoxin 5 antibody (CL488-18884) at dilution of 1:200.

CoraLite® Plus 488-conjugated Glutaredoxin 5 Polyclonal antibody

Glutaredoxin 5 Polyclonal Antibody for IF/ICC
Cat No. CL488-18884

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IF/ICC

别名

C14orf87, FLB4739, GLRX 5, GLRX5, Glutaredoxin-related protein 5, mitochondrial

缓冲液配方:  PBS, Proclin 300, BSA, Glycerol
PBS, Proclin 300, BSA, Glycerol
偶联物:  CoraLite® Plus 488
规格价格库存

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经过测试的应用

Positive IF/ICC detected inMCF-7 cells
For other applications, we recommend the unconjugated version of this antibody, 18884-1-AP

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-18884 targets Glutaredoxin 5 in IF/ICC applications and shows reactivity with human, mouse samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag13445

Product name: Recombinant human GLRX5 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-157 aa of BC023528

Sequence: MSGSLGRAAAALLRWGRGAGGGGLWGPGVRAAGSGAGGGGSAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVRDYAAYNVLDDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIHSTLLDEKKDQDSK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glutaredoxin 5
别名 C14orf87, FLB4739, GLRX 5, GLRX5, Glutaredoxin-related protein 5, mitochondrial
计算分子量 157 aa, 17 kDa
观测分子量10-15 kDa
GenBank蛋白编号BC023528
基因名称 GLRX5
Gene ID (NCBI) 51218
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ86SX6
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Glutaredoxin 5 (GLRX5) is an essential protein engaging in mitochondrial iron-sulfur cluster (ISC) transfers to iron regulatory protein (IRP), m-aconitase, and ferrochelatase. GLRX5 deficiency impairs heme biosynthesis, causing sideroblastic anemia and variant nonketotic hyperglycinemia in humans. Mutations of GLRX5 lead to distinct effects on downstream ISC biosynthesis and maturation.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 Glutaredoxin 5 antibody CL488-18884Download protocol
Standard Protocols
Click here to view our Standard Protocols
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