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验证数据展示

  • IF Staining of human tonsillitis using CL555-67075

    IF Staining of human tonsillitis using CL555-67075

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®555 Endoglin/CD105 antibody (CL555-67075, Clone: 2D5E8 ) at dilution of 1:600.

  • IF Staining of human tonsillitis using CL555-67075

    IF Staining of human tonsillitis using CL555-67075

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®555 Endoglin/CD105 antibody (CL555-67075, Clone: 2D5E8 ) at dilution of 1:600.

CoraLite®555-conjugated Endoglin/CD105 Monoclonal antibody

Endoglin/CD105 Monoclonal Antibody for IF-P
Cat No. CL555-67075

产品说明书

CloneNo. 2D5E8

宿主/亚型

Mouse / IgG2b

种属反应性

Human

应用

IF-P

别名

CD105, END, Endoglin, ENG, HHT1, ORW, ORW1, 2D5E8

缓冲液配方:  PBS, Proclin 300, BSA, Glycerol
PBS, Proclin 300, BSA, Glycerol
偶联物:  CoraLite®555
规格价格库存

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经过测试的应用

Positive IF-P detected inhuman tonsillitis tissue, human breast cancer tissue
Planning an IHC experiment? We recommend our IHCeasy Endoglin/CD105 Ready-To-Use IHC Kit. Endoglin/CD105 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67075-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:300-1:1200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL555-67075 targets Endoglin/CD105 in IF-P applications and shows reactivity with Human samples.

经测试应用 IF-P Application Description
经测试反应性 Human
免疫原

CatNo: Ag27837

Product name: Recombinant human Endoglin/CD105 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 33-221 aa of BC014271

Sequence: QPVGPERGEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHIL

种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 endoglin
别名 CD105, END, Endoglin, ENG, HHT1, ORW, ORW1, 2D5E8
计算分子量 71 kDa
观测分子量 95-100 kDa
GenBank蛋白编号BC014271
基因名称 CD105
Gene ID (NCBI) 2022
RRIDAB_2919700
偶联类型 CoraLite®555 Fluorescent Dye
最大激发/发射波长557 nm / 570nm
形式Liquid
纯化方式Protein A purification
UNIPROT IDP17813
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

实验方案

Product Specific Protocols
IF protocol for CL555 Endoglin/CD105 antibody CL555-67075Download protocol
Standard Protocols
Click here to view our Standard Protocols
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