CoraLite®594-conjugated BBS5 Monoclonal antibody
BBS5 Monoclonal Antibody for IF-P
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse
Applications
IF-P
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
4G8E12
验证数据展示
经过测试的应用
| Positive IF detected in | human kidney tissue |
For other applications, we recommend the unconjugated version of this antibody, 66136-1-Ig
推荐稀释比
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
The immunogen of CL594-66136 is BBS5 Fusion Protein expressed in E. coli.
| Tested Applications | IF-P |
| Tested Reactivity | human, mouse |
| Immunogen | BBS5 fusion protein Ag6844 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | Bardet-Biedl syndrome 5 |
| Synonyms | Bardet Biedl syndrome 5, BBS5 |
| Calculated Molecular Weight | 39 kDa |
| GenBank Accession Number | BC044593 |
| Gene Symbol | BBS5 |
| Gene ID (NCBI) | 129880 |
| RRID | AB_2919953 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q8N3I7 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
背景介绍
BBS5 encodes a protein that has been directly linked to Bardet-Biedl syndrome. Bardet-Biedl syndrome (BBS) is an autosomal recessive condition characterised by rod-cone dystrophy, postaxial polydactyly, central obesity, mental retardation, hypogonadism, and renal dysfunction. Other associated clinical findings in BBS patients include diabetes, hypertension and congenital heart defects. BBS expression varies both within and between families and diagnosis is often difficult. Experimentation in non-human eukaryotes suggests that BBS5 is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 BBS5 antibody CL594-66136 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |