YY2 Monoclonal antibody

YY2 Monoclonal Antibody for WB, ELISA
Cat No. 66839-1-Ig

产品说明书

CloneNo. 1C11A7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, ELISA

1C11A7, Transcription factor YY2, Yin and yang 2, YY 2, YY-2

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inhuman kidney tissue, human placenta tissue, MCF-7 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

66839-1-Ig targets YY2 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB
经测试反应性 human
文献引用反应性human
免疫原 YY2 fusion protein Ag25373 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 YY2 transcription factor
别名 1C11A7, Transcription factor YY2, Yin and yang 2, YY 2, YY-2
计算分子量 372 aa, 46 kDa
观测分子量 46 kDa
GenBank蛋白编号BC137217
基因名称 YY2
Gene ID (NCBI) 404281
RRIDAB_2882182
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDO15391
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

YY2 (Yin-Yang 2) encodes a zinc finger transcription factor similarity to the well-characterized YY1 that locating to nucleus. Both proteins recognize an identical DNA-binding motifs with a high homologous Zinc Finger region, and these transcription factors can act as activators or repressors when bound to DNA (PMID:26350623). It is reported that YY2 is placental mammal-specific and is absent in marsupial and non-mammalian vertebrate species (PMID:16377127). YYs are play an important role in multiple developmental processes , such as implantation, cell differentiation, X inactivation, imprinting and organogenesis (PMID:27191592). YY2 is expressed in kindey, liver, spleen and testicle but not in the colon (PMID:15087442). A 41kDa band could be detected.

实验方案

Product Specific Protocols
WB protocol for YY2 antibody 66839-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Cell Death Dis

REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis.

Authors - Yunshang Chen
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