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验证数据展示

  • IF Staining of mouse brain using CL488-67710

    IF Staining of mouse brain using CL488-67710

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite® Plus 488 TNC/Tenascin-C antibody (CL488-67710, Clone: 1F7G8 ) at dilution of 1:200.

CoraLite® Plus 488-conjugated TNC/Tenascin-C Monoclonal antibody

TNC/Tenascin-C Monoclonal Antibody for IF-P
Cat No. CL488-67710

产品说明书

CloneNo. 1F7G8

宿主/亚型

Mouse / IgG1

种属反应性

Human, Mouse, Rat

应用

IF-P

别名

Cytotactin, GMEM, GP 150 225, Hexabrachion, HXB, JI, Myotendinous antigen, Neuronectin, Tenascin, tenascin C, TN, TN C, TNC

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inmouse brain tissue
Planning an IHC experiment? We recommend our IHCeasy TNC/Tenascin-C Ready-To-Use IHC Kit. TNC/Tenascin-C primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67710-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67710 targets TNC/Tenascin-C in IF-P applications and shows reactivity with Human, Mouse, Rat samples.

经测试应用 IF-P Application Description
经测试反应性 Human, Mouse, Rat
免疫原 TNC/Tenascin-C fusion protein Ag21412 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 tenascin C
别名 Cytotactin, GMEM, GP 150 225, Hexabrachion, HXB, JI, Myotendinous antigen, Neuronectin, Tenascin, tenascin C, TN, TN C, TNC
计算分子量 2201 aa, 241 kDa
观测分子量260 kDa
GenBank蛋白编号BC151843
基因名称 Tenascin C
Gene ID (NCBI) 3371
RRIDAB_2934562
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP24821
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Tenascin-C (TNC) is a large hexameric extracellular matrix glycoprotein of the tenascin family (PMID: 21818551). It is a multimodular protein containing multiple epidermal growth factor (EGF)-like repeats and fibronectin type III (FN III) domains (PMID: 1719530). Tenascin-C is highly expressed during embryonic development, particularly in the developing central nervous system, around motile cells and at epithelial-mesenchymal interaction sites (PMID: 25738825). In adult tissues, the expression and the distribution of TNC are typically limited under normal physiological conditions. It is upregulated during injury, inflammation, regeneration, and cancer (PMID: 7694605; 25120494). Tenascin-C is a diverse protein that can produce different functions including regulating cell adhesion, migration and proliferation.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TNC/Tenascin-C antibody CL488-67710Download protocol
Standard Protocols
Click here to view our Standard Protocols