验证数据展示
经过测试的应用
| Positive IHC detected in | Human lung cancer （Adenocarcinoma） Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
Biotin-87837 targets TMED1 in IHC applications and shows reactivity with human samples.
| 经测试应用 | IHC Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Eg5903 Product name: Recombinant human TMED1 protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 24-194 aa of NM_006858 Sequence: AGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVN 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | transmembrane emp24 protein transport domain containing 1 |
| 别名 | IL1RL1L, IL1RL1LG, Interleukin-1 receptor-like 1 ligand, p24 family protein gamma-1, p24gamma1 |
| 计算分子量 | 25 kDa |
| GenBank蛋白编号 | NM_006858 |
| 基因名称 | TMED1 |
| Gene ID (NCBI) | 11018 |
| 偶联类型 | Biotin |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q13445 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Transmembrane p24 trafficking protein 1 (TMED1) belongs to the TMED protein family, also known as the p24 family, and plays a part in protein vesicular trafficking. As the critical regulator of protein trafficking along the secretory pathway, the TMED proteins influence the composition, structure, and function of the endoplasmic reticulum and the Golgi apparatus. Disruption of the secretory pathway could affect cell differentiation and survival, ultimately resulting in disease.(PMID: 38392302)
实验方案
| Product Specific Protocols | |
|---|---|
| IHC protocol for Biotin TMED1 antibody Biotin-87837 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
