验证数据展示
产品信息
84064-6-PBS targets TICAM2 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IHC, IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | toll-like receptor adaptor molecule 2 |
| 别名 | 241186C12, MyD88-4, Putative NF-kappa-B-activating protein 502, TICAM 2, TICAM-2 |
| 计算分子量 | 27 kDa |
| GenBank蛋白编号 | NM_021649 |
| 基因名称 | TICAM2 |
| Gene ID (NCBI) | 353376 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q86XR7 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TICAM2, also named TIRAP3, TIRP, and TRAM, is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1. TICAM2 is involved in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS.
