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CoraLite®594-conjugated TELO2 Monoclonal antibody

TELO2 Monoclonal Antibody for IF/ICC

Host / Isotype

Mouse / IgG1

Reactivity

human, rat

Applications

IF/ICC

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

3H10F4

Cat No : CL594-66077

Print datasheet

Synonyms

CLK2, DKFZp434A073, FLJ10924, hCLK2, KIAA0683, Protein clk 2 homolog, TEL2, TELO2

验证数据展示

  • IF Staining of HepG2 using CL594-66077

    IF Staining of HepG2 using CL594-66077

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CL594-66077 (TELO2 antibody) at dilution of 1:100.

经过测试的应用

Positive IF detected inHepG2 cells
For other applications, we recommend the unconjugated version of this antibody, 66077-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of CL594-66077 is TELO2 Fusion Protein expressed in E. coli.

Tested Applications IF/ICC
Tested Reactivity human, rat
Immunogen TELO2 fusion protein Ag8834 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name TEL2, telomere maintenance 2, homolog (S. cerevisiae)
Synonyms CLK2, DKFZp434A073, FLJ10924, hCLK2, KIAA0683, Protein clk 2 homolog, TEL2, TELO2
Calculated Molecular Weight 837 aa, 92 kDa
Observed Molecular Weight 92 kDa
GenBank Accession NumberBC017188
Gene Symbol TELO2
Gene ID (NCBI) 9894
RRIDAB_2883503
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9Y4R8
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TELO2 gene encodes a telomere length regulation protein TEL2 homolog. TELO2 may be involved in telomere length regulation and can form TTT complex with TTI1 and TTI2. TTT complex is required to stabilize protein levels of PIKK family proteins and is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and MMC. The activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals, can be promoted, stabilized and maintained by TELO2.

实验方案

Product Specific Protocols
IF protocol for CL594 TELO2 antibody CL594-66077Download protocol
Standard Protocols
Click here to view our Standard Protocols