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TBC1D2B Polyclonal antibody, PBS Only

TBC1D2B Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 24462-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IP, Indirect ELISA

TBC1 domain family member 2B, TBC1 domain family, member 2B

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存


产品信息

24462-1-PBS targets TBC1D2B in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag19632

Product name: Recombinant human TBC1D2B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 324-655 aa of BC152465

Sequence: KDEVIIKLSEGEGNGPPPTVAPSSPSVVPVARDQLELDRLKDNLQGYKTQNKFLNKEILELSALRRNAERRERDLMAKYSSLEAKLCQIESKYLILLQEMKTPVCSEDQGPTREVIAQLLEDALQVESQEQPEQAFVKPHLVSEYDIYGFRTVPEDDEEEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEV

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 TBC1 domain family, member 2B
别名 TBC1 domain family member 2B, TBC1 domain family, member 2B
计算分子量 963 aa, 110 kDa
观测分子量 120-125 kDa
GenBank蛋白编号BC152465
基因名称 TBC1D2B
Gene ID (NCBI) 23102
RRIDAB_3742115
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UPU7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TBC1 domain family member 2B (TBC1D2B) contains a functional canonical LIR motif and acts at an early stage of autophagy by binding to both LC3/GABARAP and ATG12 conjugation complexes (PMID: 38226533). When there is a high protein level of RAB22A on early endosome, TBC1D2B is recruited and acts as a brake to prevent early endosomes from maturing into late endosomes (PMID: 39051763).

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