验证数据展示
产品信息
82755-3-PBS targets SNAI2/SLUG in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | SNAI2/SLUG fusion protein Ag2773 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | snail homolog 2 (Drosophila) |
别名 | SNAI2, Protein snail homolog 2, SLUG, SLUGH, SLUGH1 |
计算分子量 | 268 aa, 30 kDa |
观测分子量 | 30-35 kDa |
GenBank蛋白编号 | BC015895 |
基因名称 | SLUG |
Gene ID (NCBI) | 6591 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | O43623 |
储存缓冲液 | PBS only, pH 7.3. |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SNAI2 belongs to the Snail family of zinc finger transcription factors, which shares an evolutionarily conserved role in mesoderm formation in vertebrates and invertebrates. It tiggers epithelial-mesenchymal transitions and has a crucial role in developmental processes. Also it is a transcriptional reperssor in mediating RAF-induced expression of TJ protein, occludin(OCLN) and subsequent oncogenic transformation of epithelial cells.