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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 83771-5-RR (same clone as 83771-5-PBS)

    WB analysis using 83771-5-RR (same clone as 83771-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83771-5-RR (SMUG1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83771-5-PBS in a different storage buffer formulation.

  • FC experiment of U-2 OS using 83771-5-RR (same clone as 83771-5-PBS)

    FC experiment of U-2 OS using 83771-5-RR (same clone as 83771-5-PBS)

    1x10^6 U-2 OS were intracellularly stained with 0.25 ug SMUG1 Recombinant antibody (83771-5-RR, Clone:240817E4) and APC-Conjugated Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed and permeabilized with True-Nuclear Transcription Factor Buffer Set. This data was developed using the same antibody clone with 83771-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83771-5-RR

    Affinity and Kinetic Characterization of 83771-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83771-5-RR against Human SMUG1 were performed. The affinity constant is below 1 pM.

SMUG1 Recombinant antibody, PBS Only

SMUG1 Uni-rAbTM Recombinant Antibody for WB, FC (Intra), ELISA
Cat No. 83771-5-PBS

产品说明书

CloneNo. 240817E4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, FC (Intra), ELISA

别名

UNG3, Single-strand selective monofunctional uracil DNA glycosylase, HMUDG, FDG, EC:3.2.2.-

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83771-5-PBS targets SMUG1 in WB, FC (Intra), ELISA applications and shows reactivity with human samples.

经测试应用 WB, FC (Intra), ELISA Application Description
经测试反应性 human
免疫原 SMUG1 fusion protein Ag13934 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 single-strand-selective monofunctional uracil-DNA glycosylase 1
别名 UNG3, Single-strand selective monofunctional uracil DNA glycosylase, HMUDG, FDG, EC:3.2.2.-
计算分子量 177 aa, 20 kDa
观测分子量30 kDa
GenBank蛋白编号BC000417
基因名称 SMUG1
Gene ID (NCBI) 23583
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ53HV7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

UNG(Uracil-DNA glycosylase) removes uracil in DNA resulting from deamination of cytosine or replicative incorporation of dUMP instead of dTMP. Thus, UNG plays a role in suppressing GC-to-AT transition mutations.The UNG gene encodes 2 isoforms that are individually targeted to the mitochondria and the nucleus(PMID:12369930).Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5).