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验证数据展示

  • IHC staining of mouse brain using 83412-4-RR (same clone as 83412-4-PBS)

    IHC staining of mouse brain using 83412-4-RR (same clone as 83412-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 83412-4-RR (same clone as 83412-4-PBS)

    IHC staining of mouse brain using 83412-4-RR (same clone as 83412-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 83412-4-RR (same clone as 83412-4-PBS)

    IHC staining of rat brain using 83412-4-RR (same clone as 83412-4-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 83412-4-RR (same clone as 83412-4-PBS)

    IHC staining of rat brain using 83412-4-RR (same clone as 83412-4-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83412-4-RR

    Affinity and Kinetic Characterization of 83412-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83412-4-RR against Human SLC6A7 were performed. The affinity constant is below 1 pM.

SLC6A7 Recombinant antibody, PBS Only

SLC6A7 Uni-rAbTM Recombinant Antibody for IHC, ELISA
Cat No. 83412-4-PBS

产品说明书

CloneNo. 240395H5

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, ELISA

别名

Sodium-dependent proline transporter, PROT, 240395H5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83412-4-PBS targets SLC6A7 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 SLC6A7 fusion protein Ag34413 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
别名 Sodium-dependent proline transporter, PROT, 240395H5
计算分子量 636 aa, 71 kDa
GenBank蛋白编号BC093785
基因名称 SLC6A7
Gene ID (NCBI) 6534
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ99884
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC6A7 also known as PROT, belongs to the solute Carrier 6 gene family. SLC6A7 is a high-affinity mammalian brain L-proline transporter, which is different from other sodium-dependent plasma membrane carriers, and has unique pharmacological specificity, kinetic properties, and ionic requirements. SLC6A7 is a brain specific sodium (and chloride)-dependent proline transporter, that terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals(PMID: 7651355).