验证数据展示
经过测试的应用
| Positive WB detected in | mouse kidney tissue, human kidney tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
87757-1-RR targets SLC22A3 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | solute carrier family 22 (extraneuronal monoamine transporter), member 3 |
| 别名 | EMT, EMTH, OCT3 |
| 计算分子量 | 61KD |
| 观测分子量 | 61 kDa |
| GenBank蛋白编号 | NM_021977 |
| 基因名称 | SLC22A3 |
| Gene ID (NCBI) | 6581 |
| RRID | AB_3745734 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O75751 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Solute carrier family 22 member 3 (SLC22A3) is also named Extraneuronal monoamine transporter (EMT) and Organic cation transporter 3 (OCT3). It belongs to the SLC22 transporter family. SLC22A3 is a high-capacity, low-affinity transporter for the neurotransmitters norepinephrine, epinephrine, dopamine, serotonin, and histamine. SLC22A3 plays important roles in interorgan and interorganism small-molecule communication, and also regulates local and overall homeostasis in the body (PMID: 37626799). OCT3 is more widely expressed than OCT1 and OCT2. OCT3 expression is widespread and can be found in the skeletal muscle, heart, brain, placenta, cornea, retina, iris, liver, kidney, and vascular endothelial cells (PMID: 29309257, PMID: 2169772).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SLC22A3 antibody 87757-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
