验证数据展示
产品信息
87757-1-PBS targets SLC22A3 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | solute carrier family 22 (extraneuronal monoamine transporter), member 3 |
| 别名 | EMT, EMTH, OCT3 |
| 计算分子量 | 61KD |
| 观测分子量 | 61 kDa |
| GenBank蛋白编号 | NM_021977 |
| 基因名称 | SLC22A3 |
| Gene ID (NCBI) | 6581 |
| RRID | AB_3745734 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O75751 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Solute carrier family 22 member 3 (SLC22A3) is also named Extraneuronal monoamine transporter (EMT) and Organic cation transporter 3 (OCT3). It belongs to the SLC22 transporter family. SLC22A3 is a high-capacity, low-affinity transporter for the neurotransmitters norepinephrine, epinephrine, dopamine, serotonin, and histamine. SLC22A3 plays important roles in interorgan and interorganism small-molecule communication, and also regulates local and overall homeostasis in the body (PMID: 37626799). OCT3 is more widely expressed than OCT1 and OCT2. OCT3 expression is widespread and can be found in the skeletal muscle, heart, brain, placenta, cornea, retina, iris, liver, kidney, and vascular endothelial cells (PMID: 29309257, PMID: 2169772).
