验证数据展示
经过测试的应用
Positive FC (Intra) detected in | HepG2 cells |
推荐稀释比
应用 | 推荐稀释比 |
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Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL594-11871 targets SH2D1B in FC (Intra) applications and shows reactivity with human, mouse, rat samples.
经测试应用 | FC (Intra) Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | SH2D1B fusion protein Ag2454 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | SH2 domain containing 1B |
别名 | EAT 2, EAT2, EAT-2, EWS/FLI1-activated transcript 2, SH2 domain containing 1B |
计算分子量 | 132 aa, 15 kDa |
观测分子量 | 15 kDa |
GenBank蛋白编号 | BC022407 |
基因名称 | SH2D1B |
Gene ID (NCBI) | 117157 |
偶联类型 | CoraLite®594 Fluorescent Dye |
最大激发/发射波长 | 588 nm / 604 nm |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | O14796 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SH2D1B, also named as EAT2, an adaptor expressed in innate immune cells, including natural killer (NK) cells. It plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. EAT-2 overexpression would enhance the innate immune responses and also result in more potent Carcinoembryonic antigen-specific adaptive immune responses.
实验方案
Product Specific Protocols | |
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FC protocol for CL594 SH2D1B antibody CL594-11871 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |