验证数据展示
产品信息
30855-1-PBS targets SETD4 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag33842 Product name: Recombinant human SETD4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-50 aa of BC002898 Sequence: MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | SET domain containing 4 |
| 别名 | C21orf18, C21orf27, SET domain containing 4, SETD 4 |
| 计算分子量 | 440 aa, 50 kDa |
| 观测分子量 | 40 kDa |
| GenBank蛋白编号 | BC002898 |
| 基因名称 | SETD4 |
| Gene ID (NCBI) | 54093 |
| RRID | AB_3742378 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9NVD3 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
As a lysine methyl-transferase of histone, SET domain-containing protein 4 (SETD4) has been reported to play a role in cell proliferation by controlling related gene expressions . Limited reports reveal that SETD4 is not only indispensable for embryonic neurogenesis, development and regeneration of pancreatic and intestinal organs, regulation of bone marrow mesenchymal stem cells, and modulation of inflammatory cytokines of macrophages, but also involved in the tumorigenesis, progression, and chemotherapy resistance of various tumors, including liver cancer, breast cancer, lymphoma and Non-small Cell Lung Cancer. (PMID: 35545041, PMID: 36027907, PMID: 37879429)
