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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • WB analysis using 83594-4-RR (same clone as 83594-4-PBS)

    WB analysis using 83594-4-RR (same clone as 83594-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83594-4-RR (SENP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83594-4-PBS in a different storage buffer formulation.

  • IHC staining of human ovarian cancer using 83594-4-RR (same clone as 83594-4-PBS)

    IHC staining of human ovarian cancer using 83594-4-RR (same clone as 83594-4-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovarian cancer slide using 83594-4-RR (SENP1 antibody) at dilution of 1:800 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83594-4-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SENP1 antibody included
  • Affinity and Kinetic Characterization of 83594-4-RR

    Affinity and Kinetic Characterization of 83594-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83594-4-RR against Human SENP1 were performed. The affinity constant is below 1 pM.

    {{ptg:ProductFeaturesInfo}}

SENP1 Recombinant monoclonal antibody, PBS Only

SENP1 Uni-rAb® Recombinant Antibody for WB, IHC, ELISA
Cat No. 83594-4-PBS

产品说明书

CloneNo. 240478D3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

别名

SuPr2, SuPr 2, Sentrin specific protease 1, SENP 1, 240478D3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy® SENP1 Ready-To-Use IHC Kit. SENP1 primary antibody included.

产品信息

83594-4-PBS targets SENP1 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag18028

Product name: Recombinant human SENP1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-331 aa of BC045639

Sequence: MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREVYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 SUMO1/sentrin specific peptidase 1
别名 SuPr2, SuPr 2, Sentrin specific protease 1, SENP 1, 240478D3
计算分子量 644 aa, 73 kDa
观测分子量73 kDa
GenBank蛋白编号BC045639
基因名称 SENP1
Gene ID (NCBI) 29843
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ9P0U3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SENP1, Sentrin-specific protease 1, is a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. SENP1 catalyzes two functions in the SUMO pathway (PMID: 29506078).The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins (PMID: 16253240). SENP1 is located in the nucleus and cytosol.