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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 67750-1-Ig (same clone as 67750-1-PBS)

    WB analysis using 67750-1-Ig (same clone as 67750-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67750-1-Ig (RUVBL1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67750-1-PBS in a different storage buffer formulation.

  • WB analysis using 67750-1-Ig (same clone as 67750-1-PBS)

    WB analysis using 67750-1-Ig (same clone as 67750-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67750-1-Ig (RUVBL1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67750-1-PBS in a different storage buffer formulation.

RUVBL1 Monoclonal antibody, PBS Only

RUVBL1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67750-1-PBS

产品说明书

CloneNo. 1F2D9

宿主/亚型

Mouse / IgG1

种属反应性

Human, rat

应用

WB, Indirect ELISA

别名

49 kDa TBP interacting protein, ECP 54, ECP54, INO80 complex subunit H, INO80H, Nuclear matrix protein 238, PONTIN, Pontin 52, Pontin52, RuvB like 1, RuvB like 1 (E. coli), RUVBL1, RVB1, TAP54 alpha, TIH1, TIP49, TIP49A

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy RUVBL1 Ready-To-Use IHC Kit. RUVBL1 primary antibody included.

产品信息

67750-1-PBS targets RUVBL1 in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, rat
免疫原 RUVBL1 fusion protein Ag16688 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 RuvB-like 1 (E. coli)
别名 49 kDa TBP interacting protein, ECP 54, ECP54, INO80 complex subunit H, INO80H, Nuclear matrix protein 238, PONTIN, Pontin 52, Pontin52, RuvB like 1, RuvB like 1 (E. coli), RUVBL1, RVB1, TAP54 alpha, TIH1, TIP49, TIP49A
计算分子量 456 aa, 50 kDa
观测分子量50 kDa
GenBank蛋白编号BC002993
基因名称 RUVBL1
Gene ID (NCBI) 8607
RRIDAB_2918519
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9Y265
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RUVBL1 is a member of the AAA (ATPase associated with diverse cellular activities) family of proteins that is associated with several chromatin-remodelling complexes and has important roles in transcriptional regulation, the DNA damage response, telomerase activity, snoRNP assembly, cellular transformation and cancer metastasis[PMID: 21617703]. It consists of 456 amino acids (50 kDa) and interacts with TATA-binding protein (TBP), which is a central component for transcriptional regulation by forming complexes with various transcription regulators. RUVBL1 is a component of a large nuclear protein complex, possibly the RNA polymerase II holoenzyme. RUVBL1 is also highly homologous to RuvB proteins that function as a DNA helicase promote branch migration of the Holliday junction[PMID: 9588198].