RAD50 Recombinant antibody, PBS Only

RAD50 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84969-4-PBS

产品说明书

CloneNo. 242541A5

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

242541A5, hRad50, RAD50 homolog (S. cerevisiae)

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

84969-4-PBS targets RAD50 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 RAD50 fusion protein Ag29949 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 RAD50 homolog (S. cerevisiae)
别名 242541A5, hRad50, RAD50 homolog (S. cerevisiae)
计算分子量 154 kDa
观测分子量 154 kDa
GenBank蛋白编号NM_005732
基因名称 RAD50
Gene ID (NCBI) 10111
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ92878
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RAD50 belongs to the ABC-ATPase protein family that concurs in forming the Nucleotide Binding Domain (NBD). ATP binding to Rad50 induces a conformational change that dramatically increases the Rad50 NBD affinity for itself, allowing for its dimerization (PMID: 37569756). The Mre11-Rad50 (MR) complex has key functions in the detection, signaling and repair of DNA breaks (PMID: 35501303).

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