验证数据展示
产品信息
68389-1-PBS targets RAB33A in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, rat, mouse, pig, rabbit samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, rat, mouse, pig, rabbit |
免疫原 | RAB33A fusion protein Ag33188 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | RAB33A, member RAS oncogene family |
别名 | RAB33A, RabS10, Ras related protein Rab 33A, Small GTP binding protein S10 |
计算分子量 | 27 kDa |
GenBank蛋白编号 | BC009996 |
基因名称 | RAB33A |
Gene ID (NCBI) | 9363 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q14088 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Ras-related protein Rab-33A (RAB33A) is also named as RABS10, and belongs to the small GTPase superfamily and the Rab family. RAB33A is an X-linked gene that is expressed in brain, lymphocytes, and normal melanocytes, but is downregulated in melanoma cells. In the brain, RAB33A is present throughout the cortex, as well as in the hippocampal CA fields (PMID:16810302). RAB33A is expressed in cells, including neurons, lymphocytes, melanocytes and parotid acinar cells (PMID:16810302, PMID:25871792). In cultured rat hippocampal neurons, RAB33A is localized to the Golgi apparatus and post-Golgi vesicles transported along axons (PMID:22972995).In addition, RAB33A interacts with singar1/RUFY3, which suppresses the formation of surplus axons in cultured hippocampal neurons (PMID:21737958, PMID:17439943).