验证数据展示
产品信息
87513-1-PBS targets Phospho-Filamin A (Ser2152) in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | filamin A, alpha (actin binding protein 280) |
| 别名 | p-Filamin A (S2152), p-Filamin A Ser2152, p-FLNA Ser2152, Phospho Filamin A (Ser2152), Phospho FLNA (Ser2152) |
| 计算分子量 | 2647 aa, 280 kDa |
| 观测分子量 | 280 kDa |
| GenBank蛋白编号 | NM_001110556 |
| 基因名称 | FLNA |
| Gene ID (NCBI) | 2316 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P21333 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FLNA encodes a 280 kDa widely expressed actin binding protein called filamin A which can crosslinks actin filaments and links actin filaments to membrane glycoproteins to form a three-dimensional network. Phospho-Filamin A (Ser2152) is a phosphorylated form of Filamin A (FLNA), which is a large actin-binding protein that plays a crucial role in organizing the cytoskeleton and transducing signals from cell membrane to the cytoskeleton. This phosphorylation event is associated with various cellular functions, including cytoskeletal remodeling, cell migration, and focal adhesion formation. (PMID:29931263)
