验证数据展示
产品信息
68240-1-PBS targets PSMA2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, pig, rat samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human, mouse, pig, rat |
免疫原 | PSMA2 fusion protein Ag5837 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | proteasome (prosome, macropain) subunit, alpha type, 2 |
别名 | HC3, Macropain subunit C3, MU, PMSA2, Proteasome component C3, PSC2, PSC3, PSMA2 |
计算分子量 | 26 kDa |
观测分子量 | 26 kDa |
GenBank蛋白编号 | BC047697 |
基因名称 | PSMA2 |
Gene ID (NCBI) | 5683 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P25787 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PSMA2 (Proteasome subunit alpha type-2) is the essential subunit that contributes to the complete assembly of 20S proteasome complex, involved in the proteolytic degradation of most intracellular proteins. It is required in spermatogenesis and generation of a subset of MHC class I-presented antigenic peptides(PMID: 34711951, PMID: 27342858). Dysregulation of PSMA2 degradation leads to tumorigenesis including cervical cancer (PMID:33684886).