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验证数据展示

  • WB analysis using 33683-1-AP (same clone as 33683-1-PBS)

    WB analysis using 33683-1-AP (same clone as 33683-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33683-1-AP (PLCB4 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33683-1-PBS in a different storage buffer formulation.

PLCB4 Polyclonal antibody, PBS Only

PLCB4 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 33683-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, EC:3.1.4.11, Phosphoinositide phospholipase C-beta-4, Phospholipase C-beta-4, PLC-beta-4

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

33683-1-PBS targets PLCB4 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag38268

Product name: Recombinant human PLCB4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 900-1110 aa of NM_182797.2

Sequence: ALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVREL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 phospholipase C, beta 4
别名 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, EC:3.1.4.11, Phosphoinositide phospholipase C-beta-4, Phospholipase C-beta-4, PLC-beta-4
计算分子量134 kDa，1175aa
观测分子量134 kDa
GenBank蛋白编号NM_182797.2
基因名称 PLCB4
Gene ID (NCBI) 5332
RRIDAB_3743049
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ15147
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Phospholipase C beta 4 (PLCB4) is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development (PMID: 35284927). Additionally, PLCB4 has an critical role in osteosarcoma progression and may serve as a novel diagnostic or therapeutic target in pediatric patients with acute myeloid leukemia (PMID: 39987366; 31788080).

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