验证数据展示
经过测试的应用
| Positive FC detected in | GM-CSF treated mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
FITC-98241 targets PD-L2/CD273 in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC Application Description |
| 经测试反应性 | mouse |
| 免疫原 | PD-L2/CD273 fusion protein Eg1842 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | programmed cell death 1 ligand 2 |
| 别名 | PD-L2/B7-DC, 241728D8, B7dc, B7-DC, Btdc |
| 计算分子量 | 28kDa |
| GenBank蛋白编号 | NM_021396.2 |
| 基因名称 | Pdcd1lg2 |
| Gene ID (NCBI) | 58205 |
| 偶联类型 | FITC Plus Fluorescent Dye |
| 最大激发/发射波长 | 495 nm / 524 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9WUL5 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Programmed cell death ligand 2 (PD-L2, also known as CD273, or B7-DC), is one of the B7 family molecules which are type I transmembrane proteins belonging to the immunoglobulin superfamily. PD-L2 was identified both by its homology to PD-L1 and by analysis of genes differentially expressed in libraries generated from dendritic cells (DC) and activated macrophages (PMID: 14515254). PD-L2 is a second ligand for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for FITC Plus PD-L2/CD273 antibody FITC-98241 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |