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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 66416-1-Ig (same clone as 66416-1-PBS)

    WB analysis using 66416-1-Ig (same clone as 66416-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66416-1-Ig (P2RX4 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66416-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 66416-1-Ig (same clone as 66416-1-PBS)

    IHC staining of human kidney using 66416-1-Ig (same clone as 66416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66416-1-Ig (P2RX4 Antibody) at dilution of 1:400 (under 10x lens). This data was developed using the same antibody clone with 66416-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 66416-1-Ig (same clone as 66416-1-PBS)

    IHC staining of human kidney using 66416-1-Ig (same clone as 66416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66416-1-Ig (P2RX4 Antibody) at dilution of 1:400 (under 40x lens). This data was developed using the same antibody clone with 66416-1-PBS in a different storage buffer formulation.

P2RX4 Monoclonal antibody, PBS Only

P2RX4 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 66416-1-PBS

产品说明书

CloneNo. 1A5A6

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse, pig, rat

应用

WB, IHC, Indirect ELISA

别名

ATP receptor, P2RX4, P2X purinoceptor 4, P2X4, P2X4R, Purinergic receptor

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66416-1-PBS targets P2RX4 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, pig, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, pig, rat
免疫原 P2RX4 fusion protein Ag4445 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 purinergic receptor P2X, ligand-gated ion channel, 4
别名 ATP receptor, P2RX4, P2X purinoceptor 4, P2X4, P2X4R, Purinergic receptor
计算分子量 388 aa, 43 kDa
观测分子量 50 kDa
GenBank蛋白编号BC033826
基因名称 P2RX4
Gene ID (NCBI) 5025
RRIDAB_2881788
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99571
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Nucleotides, the structural subunits of the nucleic acids, are also important extracellular signaling molecules. P2 receptors are a family of cell surface receptors that mediate a wide variety of physiologic effects in response to extracellular nucleotides. These receptors fall into two classes: P2X receptors, which are ligand-gated ion channels that mediate calcium and potassium fluxes in response to ATP, and P2Y receptors, which are G protein-coupled receptors (GPCRs). P2RX4 (P2X purinoceptor 4) is a receptor for ATP acting as a ligand gated ion channel. The calculated molecular weight of P2RX4 is 43 kDa, larger apparent molecular weights of 50-80 kDa have been reported, possibly due to post-translational glycosylation (PMID: 24040145, 15262999; 29382907; 12566439).