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验证数据展示

  • WB analysis using 12417-1-AP (same clone as 12417-1-PBS)

    WB analysis using 12417-1-AP (same clone as 12417-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12417-1-AP (OSBPL3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12417-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 12417-1-AP (same clone as 12417-1-PBS)

    IHC staining of human colon cancer using 12417-1-AP (same clone as 12417-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 12417-1-AP (OSBPL3 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12417-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with OSBPL3 antibody included
  • IHC staining of human colon cancer using 12417-1-AP (same clone as 12417-1-PBS)

    IHC staining of human colon cancer using 12417-1-AP (same clone as 12417-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 12417-1-AP (OSBPL3 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12417-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with OSBPL3 antibody included

OSBPL3 Polyclonal antibody, PBS Only

OSBPL3 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 12417-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

OSBP3, OSBP related protein 3, ORP-3, ORP3, ORP 3

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy® OSBPL3 Ready-To-Use IHC Kit. OSBPL3 primary antibody included.

产品信息

12417-1-PBS targets OSBPL3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag3044

Product name: Recombinant human OSBPL3 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-350 aa of BC017731

Sequence: MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSA

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 oxysterol binding protein-like 3
别名 OSBP3, OSBP related protein 3, ORP-3, ORP3, ORP 3
计算分子量 887 aa, 101 kDa
观测分子量 95-110 kDa
GenBank蛋白编号BC017731
基因名称 OSBPL3
Gene ID (NCBI) 26031
RRIDAB_2156103
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H4L5
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The oxysterol-binding protein-like (OSBPL) protein family includes nine members namely OSBPL2, OSBPL3, OSBPL5, OSBPL6, OSBPL7, OSBPL8, OSBPL9, OSBPL10, and OSBPL11. The OSBPL family proteins (OSBPLs) are located at the membrane to exchange molecules or signals between organelles and function as a necessary transporter. In addition to lipid transport, the OSBPLs are involved in the regulation of the actin cytoskeleton, cell polarity, and cell. Recently, the role of OSBPLs in cancer development has been gradually revealed. Upregulation of OSBPL3 could promote colorectal cancer. (PMID: 36918840)

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