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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of mouse heart using 83131-8-RR (same clone as 83131-8-PBS)

    WB analysis of mouse heart using 83131-8-RR (same clone as 83131-8-PBS)

    mouse heart tissue were subjected to SDS PAGE followed by western blot with 83131-8-RR (NLRP10 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83131-8-PBS in a different storage buffer formulation.

  • FC experiment of A431 using 83131-8-RR (same clone as 83131-8-PBS)

    FC experiment of A431 using 83131-8-RR (same clone as 83131-8-PBS)

    1x10^6 A431 cells were intracellularly stained with 0.25 ug Nlrp10 Recombinant Antibody (83131-8-RR, Clone:230402C1) and APC-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed and permeabilized with True-Nuclear Transcription Factor Buffer Set. This data was developed using the same antibody clone with 83131-8-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83131-8-RR

    Affinity and Kinetic Characterization of 83131-8-RR

    Biolayer interferometry (BLl) kinetic assays of 83131-8-RR against Human NLRP10 were performed. The affinity constant is 0.899 nM.

NLRP10 Recombinant antibody, PBS Only

NLRP10 Uni-rAbTM Recombinant Antibody for WB, FC (Intra), Indirect ELISA
Cat No. 83131-8-PBS

产品说明书

CloneNo. 230402C1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, FC (Intra), Indirect ELISA

别名

230402C1, CLR11.1, NACHT, LRR and PYD domains-containing protein 10, NALP10, NOD8

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83131-8-PBS targets NLRP10 in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, FC (Intra), Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 NLRP10 fusion protein Ag26402 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 NLR family, pyrin domain containing 10
别名 230402C1, CLR11.1, NACHT, LRR and PYD domains-containing protein 10, NALP10, NOD8
计算分子量 655 aa, 75 kDa
观测分子量75 kDa
GenBank蛋白编号BC104957
基因名称 NLRP10
Gene ID (NCBI) 338322
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ86W26
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NLRP10 is a member of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). NLRP10 likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5.