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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis of HT-1080 using 19916-1-AP (same clone as 19916-1-PBS)

    WB analysis of HT-1080 using 19916-1-AP (same clone as 19916-1-PBS)

    HT-1080 cells were subjected to SDS PAGE followed by western blot with 19916-1-AP (MRI1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19916-1-PBS in a different storage buffer formulation.

  • IHC staining of rat kidney using 19916-1-AP (same clone as 19916-1-PBS)

    IHC staining of rat kidney using 19916-1-AP (same clone as 19916-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 19916-1-AP (MRI1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19916-1-PBS in a different storage buffer formulation.

  • IHC staining of rat kidney using 19916-1-AP (same clone as 19916-1-PBS)

    IHC staining of rat kidney using 19916-1-AP (same clone as 19916-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 19916-1-AP (MRI1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19916-1-PBS in a different storage buffer formulation.

MRI1 Polyclonal antibody, PBS Only

MRI1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 19916-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

19916-1-PBS targets MRI1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 MRI1 fusion protein Ag13809 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
别名
计算分子量 369 aa, 39 kDa
观测分子量 45 kDa
GenBank蛋白编号BC001703
基因名称 MRI1
Gene ID (NCBI) 84245
RRIDAB_10638924
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BV20
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MRI1 is also named as MRDI and belongs to the eIF-2B alpha/beta/delta subunits family. MRI1 promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation (PMID:19620624). MRDI acts as a methylthioribose-1-phosphate (MTR-1-P) isomerase, catalyzing a critical step in methionine salvage. Second, MRDI promotes and is necessary for melanoma cell invasion, independent of its catalytic activity (PMID:23859498).