验证数据展示
产品信息
30675-1-PBS targets Lipoprotein(a) in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IHC, IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag32907 Product name: Recombinant human Lipoprotein(a) protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1835-2040 aa of NM_005577 Sequence: VSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQADIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFGTGLLKEAQLLVIENEVCNHYKYICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMRNN 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | lipoprotein, Lp(a) |
| 别名 | LPA, Lp(a), LP, Apolipoprotein(a), APOA |
| 计算分子量 | 501 kDa |
| 观测分子量 | 501 kDa |
| GenBank蛋白编号 | NM_005577 |
| 基因名称 | LPA |
| Gene ID (NCBI) | 4018 |
| RRID | AB_3742365 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P08519 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Lipoprotein(a), also known as Lp(a). The plasma concentration of human lipoprotein(a) is correlated with the risk of heart disease. A distinct feature of the Lp(a) particle is the apolipoprotein (a), which is associated with apoB-100, the main protein component of low-density lipoprotein. It is reported that apo(a), which has extensive homology to plasminogen, binds to immobilized fibronectin (PMID: 2531657). The binding of Lp(a) was localized to the C-terminal heparin-binding domain of fibronectin. It is enriched in liver tissue. The N-glycans are complex biantennary structures present in either a mono- or disialylated state.
