验证数据展示
产品信息
17658-1-PBS targets LGR6 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IHC, ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | LGR6 fusion protein Ag11909 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | leucine-rich repeat-containing G protein-coupled receptor 6 |
别名 | VTS20631, UNQ6427/PRO21331, Leucine-rich repeat-containing G-protein coupled receptor 6, GPCR |
计算分子量 | 915 aa, 99 kDa |
观测分子量 | 104 kDa |
GenBank蛋白编号 | BC047905 |
基因名称 | LGR6 |
Gene ID (NCBI) | 59352 |
RRID | AB_2135163 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9HBX8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LGR6 (Leucine-rich repeat-containing G-protein coupled receptor 6) is a seven-transmembrane protein. LGR6 is a high affinity receptor of R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. It potentially functions as a tumor suppressor. (PMID: 20223988; 20417836; 22615920)