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LARP7 Polyclonal antibody, PBS Only

LARP7 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 17067-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

HDCMA18P, hLARP7, La related protein 7, La-related protein 7, PIP7S

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存


Planning an IHC experiment? We recommend our IHCeasy LARP7 Ready-To-Use IHC Kit. LARP7 primary antibody included.

产品信息

17067-1-PBS targets LARP7 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag10891

Product name: Recombinant human LARP7 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 83-331 aa of BC006981

Sequence: LTTDGKLIARALRSSAVVELDLEGTRIRRKKPLGERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRMKKEDNIQAKEENMDTSNTSISKMKRSRPTSEGSDIESTEPQKQCSKKKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSKVKKIIQKDIIKEASEASKE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 La ribonucleoprotein domain family, member 7
别名 HDCMA18P, hLARP7, La related protein 7, La-related protein 7, PIP7S
计算分子量 582 aa, 67 kDa
观测分子量 67 kDa
GenBank蛋白编号BC006981
基因名称 LARP7
Gene ID (NCBI) 51574
RRIDAB_2132693
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ4G0J3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LARP7 belongs to the LARP RNA-binding protein family, which includes the lupus LA antigen gene, and modulates the metabolism and function of a variety of RNA species [PMID:20138158]. LARP7 binds to the 7SK RNP complex, and sequesters the positive transcription elongation factor b (P-TEFb) in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. binds to and stabilizes 7sk snRNA[PMID:19416841].

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