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CoraLite® Plus 488-conjugated KIF5A Monoclonal antibody

KIF5A Monoclonal Antibody for IF/ICC

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat, pig

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1A7E3

Cat No : CL488-67009

Print datasheet

Synonyms

D12S1889, KIF5A, kinesin family member 5A, Kinesin heavy chain isoform 5A, MY050, Neuronal kinesin heavy chain, NKHC, NKHC1, SPG10

验证数据展示

  • IF Staining of PC-12 using CL488-67009

    IF Staining of PC-12 using CL488-67009

    Immunofluorescent analysis of (4% PFA) fixed PC-12 cells using CoraLite® Plus 488 KIF5A antibody (CL488-67009, Clone: 1A7E3 ) at dilution of 1:200.

经过测试的应用

Positive IF detected inPC-12 cells
For other applications, we recommend the unconjugated version of this antibody, 67009-1-Ig

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67009 targets KIF5A in IF applications and shows reactivity with Human, mouse, rat, pig samples.

Tested Applications IF/ICC
Tested Reactivity Human, mouse, rat, pig
Immunogen KIF5A fusion protein Ag15682 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name kinesin family member 5A
Synonyms D12S1889, KIF5A, kinesin family member 5A, Kinesin heavy chain isoform 5A, MY050, Neuronal kinesin heavy chain, NKHC, NKHC1, SPG10
Calculated Molecular Weight 1032 aa, 117 kDa
Observed Molecular Weight 130 kDa
GenBank Accession NumberBC146670
Gene Symbol KIF5A
Gene ID (NCBI) 3798
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ12840
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Kinesin superfamily proteins (KIFs) are microtubule-based molecular motors essential for the intracellular transport of various cargos, including organelles, proteins, and RNAs. KIF5A is expressed exclusively in neurons and transports neuronal cargoes into axons and dendrites. KIF5A mutations have been associated with Charcot-Marie-Tooth Type 2, an axonal peripheral neuropathy characterized by progressive loss of peripheral sensation and muscle wasting.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 KIF5A antibody CL488-67009Download protocol
Standard Protocols
Click here to view our Standard Protocols