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验证数据展示

  • WB analysis using 80331-1-RR (same clone as 80331-1-PBS)

    WB analysis using 80331-1-RR (same clone as 80331-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 80331-1-RR (JAK3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

  • IHC staining of human lymphoma using 80331-1-RR (same clone as 80331-1-PBS)

    IHC staining of human lymphoma using 80331-1-RR (same clone as 80331-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 80331-1-RR (JAK3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

  • IP experiment of HEK-293 using 80331-1-RR (same clone as 80331-1-PBS)

    IP experiment of HEK-293 using 80331-1-RR (same clone as 80331-1-PBS)

    IP result of anti-JAK3 (IP:80331-1-RR, 4ug; Detection:80331-1-RR 1:1000) with HEK-293 cells lysate 1640 ug. This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

JAK3 Recombinant monoclonal antibody, PBS Only

JAK3 Uni-rAb® Recombinant Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 80331-1-PBS

产品说明书

CloneNo. 3N1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IP, Indirect ELISA

别名

3N1, EC:2.7.10.2, JAK 3, JAK-3, JAKL

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

80331-1-PBS targets JAK3 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 Janus kinase 3 (a protein tyrosine kinase, leukocyte)
别名 3N1, EC:2.7.10.2, JAK 3, JAK-3, JAKL
计算分子量 1124 aa, 125 kDa
观测分子量 125 kDa
GenBank蛋白编号BC028068
基因名称 JAK3
Gene ID (NCBI) 3718
RRIDAB_2918888
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP52333
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

JAK3 is a non-receptor tyrosine kinase, predominantly expressed in hematopoietic cells and that has been implicated in the signal transduction of the common gamma chain subfamily of cytokine receptors. As a result, JAK3 plays an essential role in hematopoieisis during T cell development. JAK3 belongs to the Janus kinase family of receptor-associated tyrosine kinases located in cytoplasm adjacent to the plasma membrane. (PMID: 19747563, PMID: 33767339)

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