验证数据展示
经过测试的应用
Positive IHC detected in | human ovary tumor tissue, human pancreas cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
应用 | 推荐稀释比 |
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Immunohistochemistry (IHC) | IHC : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
21703-1-AP targets Integrin Beta 6 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | IHC, ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | Integrin Beta 6 fusion protein Ag16319 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | integrin, beta 6 |
别名 | ITGB6, Integrin beta-6, integrin, beta 6 |
计算分子量 | 788 aa, 86 kDa |
GenBank蛋白编号 | BC121178 |
基因名称 | Integrin beta 6 |
Gene ID (NCBI) | 3694 |
RRID | AB_2878906 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P18564 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ITGB6 belongs to the integrin beta chain family. ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
实验方案
Product Specific Protocols | |
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IHC protocol for Integrin Beta 6 antibody 21703-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |