验证数据展示
产品信息
87161-1-PBS targets INPPL1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | inositol polyphosphate phosphatase-like 1 |
| 别名 | EC:3.1.3.86, Inositol polyphosphate phosphatase-like protein 1, INPPL 1, INPPL-1, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 |
| 计算分子量 | 1258 aa, 139 kDa |
| 观测分子量 | 150 kDa |
| GenBank蛋白编号 | BC140853 |
| 基因名称 | INPPL1 |
| Gene ID (NCBI) | 3636 |
| RRID | AB_3745380 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O15357 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Inositol polyphosphate phosphatase-like protein 1(INPPL1) belongs to the inositol and phosphatidylinositol 5-phosphatase family, also known as SH2 domain-containing inositol 5'-phosphatase 2(SHIP2), is ubiquitous in all organizations. SHIP2 is constitutively tyrosine-phosphorylated in chronic myeloid leukemia progenitor cells. In B cells, SHIP2 was most tyrosine phosphorylated after BCR and FC-γriib crosslinking and was associated with Shc, but not after BCR stimulation alone.

