IL-1R2 Monoclonal antibody
IL-1R2 Monoclonal Antibody for IF/ICC, WB,ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse and More (1)
Applications
IF/ICC, WB,ELISA
Conjugate
Unconjugated
CloneNo.
3H4H4
验证数据展示
经过测试的应用
Positive WB detected in | HeLa cells |
Positive IF detected in | HeLa cells |
Planning an IF experiment? We recommend our CoraLite®594 conjugated versions of this antibody.
推荐稀释比
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
Immunofluorescence (IF) | IF : 1:20-1:200 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
WB | See 2 publications below |
IF | See 1 publications below |
产品信息
The immunogen of 60262-1-Ig is IL-1R2 Fusion Protein expressed in E. coli.
Tested Applications | IF/ICC, WB,ELISA |
Cited Applications | WB, IF |
Tested Reactivity | human, mouse |
Cited Reactivity | mouse, rat |
Immunogen | IL-1R2 fusion protein Ag4495 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Full Name | interleukin 1 receptor, type II |
Synonyms | CD121b, CDw121b, IL 1R 2, IL 1R beta, IL 1RT 2, IL 1RT2, IL1 Receptor 2, IL-1 Receptor 2, IL1 Receptor II, IL-1 Receptor II, IL1R2, IL-1R2, IL1RB, IL-1RII, Interleukin 1 receptor beta, Interleukin 1 receptor type 2, Interleukin 1 receptor type II |
Calculated Molecular Weight | 398 aa, 45 kDa |
Observed Molecular Weight | 45 kDa |
GenBank Accession Number | BC039031 |
Gene Symbol | IL1R2 |
Gene ID (NCBI) | 7850 |
RRID | AB_2881383 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P27930 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.
实验方案
Product Specific Protocols | |
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WB protocol for IL-1R2 antibody 60262-1-Ig | Download protocol |
IF protocol for IL-1R2 antibody 60262-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Mater Today Bio Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis | ||
Biochem Pharmacol Oridonin employs interleukin 1 receptor type 2 to treat noise-induced hearing loss by blocking inner ear inflammation |