验证数据展示
产品信息
60262-1-PBS targets IL-1R2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | IL-1R2 fusion protein Ag4495 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | interleukin 1 receptor, type II |
别名 | IL1R2, IL 1RT 2, IL 1R beta, IL 1R 2, CD121b |
计算分子量 | 398 aa, 45 kDa |
观测分子量 | 45 kDa |
GenBank蛋白编号 | BC039031 |
基因名称 | IL1R2 |
Gene ID (NCBI) | 7850 |
RRID | AB_2881383 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P27930 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.