Anti-Human IL-3RB/CD131 Rabbit Recombinant Antibody

IL-3RB/CD131 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98336-2-RR

产品说明书

CloneNo. 241823B12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

CSF2RB, CD131, CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit, IL3RB

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive FC detected inTransfected HEK-293T cells

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

98336-2-RR targets IL-3RB/CD131 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 IL-3RB/CD131 fusion protein Eg1662 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
别名 CSF2RB, CD131, CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit, IL3RB
计算分子量97kDa
GenBank蛋白编号NM_000395.3
基因名称 CSF2RB
Gene ID (NCBI) 1439
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP32927-1
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2 - 8°C. Stable for one year after shipment.

背景介绍

IL-3RB/CD131, also known as CSF2RB, is the common subunit of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5. CD131 is expressed on various immune cells, including hematopoietic progenitor cells, granulocytes, monocytes, macrophages, eosinophils, and mast cells, which plays a crucial role in mediating the effects of cytokines (PMID: 18412971). Tregs of healthy donors constitutively transcribe CSF2RB, but protein expression was much higher after TCR stimulation (PMID: 36532080, 3557440).

实验方案

Product Specific Protocols
FC protocol for IL-3RB/CD131 antibody 98336-2-RRDownload protocol
Standard Protocols
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