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Host
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Species Reactivity
0
Conjugate
0
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0
Conjugate
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验证数据展示

  • FC experiment of Transfected HEK-293T using 98336-2-RR (same clone as 98336-2-PBS)

    FC experiment of Transfected HEK-293T using 98336-2-RR (same clone as 98336-2-PBS)

    1x10^6 HEK-293T cells (left) or IL-3RB/CD131-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Human IL-3 R Beta/CD131 Rabbit RecAb (98336-2-RR, Clone:241823B12) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98336-2-PBS in a different storage buffer formulation.

  • FC experiment of Transfected HEK-293T using 98336-2-RR (same clone as 98336-2-PBS)

    FC experiment of Transfected HEK-293T using 98336-2-RR (same clone as 98336-2-PBS)

    1x10^6 HEK-293T cells(left) or IL-3RB/CD131-transfected HEK-293T cells(right) were surface stained with 0.25 ug Anti-Human IL-3 R Beta/CD131 Rabbit RecAb (98336-2-RR, Clone:241823B12)(red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98336-2-PBS in a different storage buffer formulation.

Anti-Human IL-3RB/CD131 Rabbit Recombinant Antibody, PBS Only

IL-3RB/CD131 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98336-2-PBS

产品说明书

CloneNo. 241823B12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

CSF2RB, CD131, CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit, IL3RB

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98336-2-PBS targets IL-3RB/CD131 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 IL-3RB/CD131 fusion protein Eg1662 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
别名 CSF2RB, CD131, CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit, IL3RB
计算分子量97kDa
GenBank蛋白编号NM_000395.3
基因名称 CSF2RB
Gene ID (NCBI) 1439
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP32927-1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-3RB/CD131, also known as CSF2RB, is the common subunit of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5. CD131 is expressed on various immune cells, including hematopoietic progenitor cells, granulocytes, monocytes, macrophages, eosinophils, and mast cells, which plays a crucial role in mediating the effects of cytokines (PMID: 18412971). Tregs of healthy donors constitutively transcribe CSF2RB, but protein expression was much higher after TCR stimulation (PMID: 36532080, 3557440).