PE Anti-Human IGF1R/CD221 Rabbit Recombinant Antibody

IGF1R/CD221 Recombinant Antibody for FC
Cat No. PE-98144

产品说明书

CloneNo. 241679A6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

IGF 1 receptor, IGF1R, IGF-I receptor, IGFIR, IGFR

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  PE
规格: 

-/ -


经过测试的应用

Positive FC detected inhuman peripheral blood granulocytes
Planning an IHC experiment? We recommend our IHCeasy IGF1R Ready-To-Use IHC Kit. IGF1R primary antibody included.

推荐稀释比

应用推荐稀释比
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

PE-98144 targets IGF1R/CD221 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 IGF I receptor
别名 IGF 1 receptor, IGF1R, IGF-I receptor, IGFIR, IGFR
计算分子量 1367 aa, 155 kDa
GenBank蛋白编号BC113612
基因名称 IGF1R
Gene ID (NCBI) 3480
RRIDAB_3674028
偶联类型 PE Fluorescent Dye
最大激发/发射波长496 nm, 565 nm / 578 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP08069
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

IGF1R, also named as CD221, is a receptor tyrosine kinase which mediates actions of INS-like growth factor 1 (IGF1). IGF1R binds IGF1 with high affinity and IGF2 and INS with a lower affinity, the activated IGF1R is involved in cell growth and survival control. It is crucial for tumor transformation and survival of malignant cells. IGF1R is a heterotetrameric receptor, composed of two alpha subunits (130 kDa each) and two beta subunits (~98 kDa each) (PMID: 6279656). Both the alpha and beta subunits are synthesized from a single mRNA precursor. The precursor is then glycosylated, proteolytically cleaved, and crosslinked by cysteine bonds.

实验方案

Product Specific Protocols
FC protocol for PE IGF1R/CD221 antibody PE-98144Download protocol
Standard Protocols
Click here to view our Standard Protocols
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