• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IF Staining of rat pancreas using 60931-1-Ig (same clone as 60931-1-PBS)

    IF Staining of rat pancreas using 60931-1-Ig (same clone as 60931-1-PBS)

    FFPE-rat pancreas tissue was stained with GLP1R monoclonal antibody (Cat.NO. 60931-1-Ig) at 1:500 followed by detection with Multi-rAb® Polymer HRP-Goat Anti-Rabbit/Mouse Universal Recombinant Secondary Antibody (H+L) (Cat.NO. RGAU011). CoraLite®Plus 647-Tyramide Reagent (Cat.NO. PR30025) was used for signal development (purple). The slide was then conducted HIER in pH 9.0 Tris-EDTA buffer followed by staining with INS monoclonal antibody (66198-1-Ig, 1:5000). CoraLite®Plus 488-Tyramide Reagent (Cat.NO. PR30022) were used for signal development (green). Cell nucleus (blue) were stained with DAPI. The signal from each channel was captured and merged. This data was developed using the same antibody clone with 60931-1-PBS in a different storage buffer formulation.

  • Cytometric bead array sample test of MP51365-1

    Cytometric bead array sample test of MP51365-1

    Sample test of MP51365-1, GLP1R Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60931-1-PBS. Detection antibody: 60931-2-PBS.

  • Cytometric bead array standard curve of MP51365-1

    Cytometric bead array standard curve of MP51365-1

    Cytometric bead array standard curve of MP51365-1, GLP1R Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60931-1-PBS. Detection antibody: 60931-2-PBS. Standard:Ag23529. Range: 0.391-200 ng/mL.

GLP1R Monoclonal antibody, PBS Only (Capture)

GLP1R Monoclonal Antibody for IF/ICC, Cytometric bead array, Indirect ELISA
Cat No. 60931-1-PBS

产品说明书

CloneNo. 1A4G5

宿主/亚型

Mouse / IgG1

种属反应性

human, rat

应用

IF/ICC, Cytometric bead array, Indirect ELISA

别名

GLP 1 R, GLP 1 receptor, GLP 1R, GLP-1 receptor, GLP-1R

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

60931-1-PBS targets GLP1R as part of a matched antibody pair:

MP51365-1: 60931-1-PBS capture and 60931-2-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 IF/ICC, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human, rat
免疫原

CatNo: Ag23529

Product name: Recombinant human GLP1R protein

Source: e coli.-derived, PET30a

Tag: 6*His

Domain: 26-145 aa of BC112126

Sequence: QGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLY

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 glucagon-like peptide 1 receptor
别名 GLP 1 R, GLP 1 receptor, GLP 1R, GLP-1 receptor, GLP-1R
计算分子量 463 aa, 53 kDa
GenBank蛋白编号BC112126
基因名称 GLP1R
Gene ID (NCBI) 2740
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDP43220
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GLP1R (glucagon-like peptide-1 receptor) is a G protein-coupled receptor belonging to the secretin receptor superfamily, also known as class B (PMID:34911028). GLP1R is widely distributed in pancreatic islets, muscles, the gastrointestinal tract, the lung, liver, pancreas, and other tissues or organs (PMID:35989517). Moreover, GLP1R agonist has been reported to induce autophagy of EC (Endometrial carcinoma) cells, and high GLP1R expression may be associated with good prognosis of EC patients, suggesting that GLP1R is likely to participate in the progression of EC (PMID:29907137). Moreover, regarding the molecular weight of GLP1R, research shows that the bands at ~50 kDa and ~100 kDa belong to the monomer and dimer states of GLP1R (PMID: 28609478).