验证数据展示
产品信息
98262-1-PBS targets GGGGS Linker in WB, IHC, IF/ICC, FC applications and shows reactivity with n/a samples.
经测试应用 | WB, IHC, IF/ICC, FC Application Description |
经测试反应性 | n/a |
免疫原 | Peptide 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | GGGGS Linker |
别名 | G4S, G4S link, G4S Linker, GGGGS, GS Linker |
基因名称 | |
Gene ID (NCBI) | |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
As a crucial element in the design of recombinant fusion proteins, linkers play an increasingly vital role in the construction of stable, bioactive fusion proteins (PMID: 23026637). GGGGS linker (G4S linker) is a flexible linker made of 4 glycine repeats followed by a serine amino acid (PMID:3045807). Due to its flexibility and resistance to proteases, GGGGS and its repeats are commonly used when engineering a protein, particularly in the construction of single-chain Fv (ScFv) domains expressed on the surfaces of CAR-T cells (PMID:23581628; 36874404). This antibody was raised against a synthetic peptide (GGGGSGGGGSGGGGS).