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Host
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Species Reactivity
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Species Reactivity
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0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 68051-1-Ig (same clone as 68051-1-PBS)

    WB analysis using 68051-1-Ig (same clone as 68051-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 68051-1-Ig (GAS2L1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Beta Actin Monoclonal antibody (HRP-66009) as loading control. This data was developed using the same antibody clone with 68051-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse testis using 68051-1-Ig (same clone as 68051-1-PBS)

    IHC staining of mouse testis using 68051-1-Ig (same clone as 68051-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 68051-1-Ig (GAS2L1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68051-1-PBS in a different storage buffer formulation.

GAS2L1 Monoclonal antibody, PBS Only

GAS2L1 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 68051-1-PBS

产品说明书

CloneNo. 2C6D5

宿主/亚型

Mouse / IgG1

种属反应性

Human, Mouse

应用

WB, IHC, Indirect ELISA

别名

GAR22, GAS2 like protein 1, GAS2L1, growth arrest 2 like 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

68051-1-PBS targets GAS2L1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human, Mouse
免疫原

CatNo: Ag31232

Product name: Recombinant human GAS2L1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-329 aa of BC011047

Sequence: MADPVAGIAGSAAKSVRPFRSSEAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAARALAAARPARGVAFQAHSVVPGSFMARDNVATFIGWCRVELGVPEVLMFETEDLVLRKNEKSVVLCLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTETAPAPGTPARGPRMTPSDLRNLDELVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLEHYLDKHDPCRCSSTAHRPPQPRVCTFSPQRVSPTTSPRPASPVPGSERRGSRPEMTPVSLRSTK

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 growth arrest-specific 2 like 1
别名 GAR22, GAS2 like protein 1, GAS2L1, growth arrest 2 like 1
计算分子量 73 kDa
观测分子量73 kDa
GenBank蛋白编号BC011047
基因名称 GAS2L1
Gene ID (NCBI) 10634
RRIDAB_2918793
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ99501
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GAS2L1(growth arrest‐specific 2‐like 1) is a component of the cytoskeleton that mediates the interaction between microtubules and microfilament (PMID: 34555082). GAS2L1 contains an N‐terminal actin‐binding calponin homology (CH) domain, a MT lattice‐binding Gas2‐related (GAR) domain and a C‐terminal SxIP motif, which mediates the interaction with MT plus ends via EB proteins. GAS2L1 regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (PubMed:24706950).