G-CSFR Recombinant antibody

G-CSFR Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 84827-2-RR

产品说明书

CloneNo. 242246A5

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

G-CSF receptor, G CSF receptor, G CSF R, CSF3R, CD114

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inTHP-1 cells, HL-60 cells, human placenta tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84827-2-RR targets G-CSFR in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 colony stimulating factor 3 receptor (granulocyte)
别名 G-CSF receptor, G CSF receptor, G CSF R, CSF3R, CD114
计算分子量92 kDa
观测分子量120-140 kDa
GenBank蛋白编号NM_000760.3
基因名称 G-CSFR
Gene ID (NCBI) 1441
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99062-1
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

G-CSF-R, also named as CSF3R, CD114 and GCSFR is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. It is a 130 kD to 150 kD glycoprotein single chain receptor which binds and activated by GCSF. In addition it may function in some adhesion or recognition events at the cell surface. It has been classified as a member of the hematopoietic (cytokine) receptor family, cytokine receptor class I, or the gp 130 related cytokine receptor family (although it does not apparently bind to gp 130). GCSF receptors can be found on neutrophils, myeloid leukemia cells that respond to GCSF, bone marrow cells of neutrophilic granulocyte lineage, and on placental trophoblasts. In addition, a soluble form is also expressed. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

实验方案

Product Specific Protocols
WB protocol for G-CSFR antibody 84827-2-RRDownload protocol
Standard Protocols
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