验证数据展示
Planning an IHC experiment? We recommend our IHCeasy FXYD1 Ready-To-Use IHC Kit. FXYD1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67150-1-Ig
产品信息
CL488-67150 targets FXYD1 in applications and shows reactivity with human, mouse, pig samples.
| 经测试应用 | Application Description |
| 经测试反应性 | human, mouse, pig |
| 免疫原 | FXYD1 fusion protein Ag25307 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | FXYD domain containing ion transport regulator 1 |
| 别名 | Sodium/potassium-transporting ATPase subunit FXYD1, PLM, Phospholemman/FXYD1, Phospholemman, FXYD domain-containing ion transport regulator 1 |
| 计算分子量 | 92 aa, 10 kDa |
| 观测分子量 | 15 kDa |
| GenBank蛋白编号 | BC032800 |
| 基因名称 | FXYD1 |
| Gene ID (NCBI) | 5348 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O00168 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
FXYD1, also named as PLM and Phospholemman, belongs to the FXYD family. FXYD1 induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. It may have a functional role in muscle contraction. FXYD1 is a partner protein and regulator of the Na+,K+-ATPase (Na+,K+-pump). It may play a role in the acute regulation of the Na+,K+-ATPase response to exercise. (PMID: 20595385, 21653224)